This tool generates a negative control for siRNA :
It accepts a short DNA sequence, and returns a scrambled sequence.
The scrambled sequence will have the same nucleotide composition as the input sequence and it will have passed siRNA filtering for the standart search (see Selection Criteria for more details).
Moreover, it will have no match with any mRNA of the selected organism database, and no known miRNA SEED recognition sequence.
Instructions1. Enter the siRNA hairpin name for reference (optional)
2. Enter the sense siRNA target sequence. (Spaces in the sequence will be ignored)
3. Choose the database corresponding to the target gene.